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Tuesday, April 9, 2013

Vitamin D3 and Langerhan suppression!!!

Soooooo remember how I told you about these Langerhan cells, well in my "langerhan and" searches, I found a connection. I constantly google key phrases together. When I say key phrases I mean whatever new term I am looking into with the addition of "and MTHFR", or "and B vitamins", or "and methylation". Today I googled "langerhan and B vitamins", since that is the major deficiency with MTHFR, and found this......

http://www.ncbi.nlm.nih.gov/pubmed/9627697
Concluding with :
"It is proposed that the inhibitory effects of the vitamin D3 on Langerhans cells may induce immunosuppression in the skin."

What does this mean? Why should we care? Well remember, Langerhan cells are antigen producing immune cells in the skin. This means they produce an allergic or inflammatory response in the skin. If we have too many of these we have inflammatory skin issues, in our case....eczema. I have noticed a consistent response in J's inflammation with the introduction of D3 drops. The other day I didn't realize the drops started and I gave her too many. The next day she was glowing and so much less red. Does this mean D3 is the cure to eczema, probably not. Do I think D3 is a must for ALL atopic kids, absolutely. I am glad to have found the "why" D3 was such a game changer for us.

In addition, the difficulty with starting to find the "why" in things that are not working correctly, is the common realization of our own role in the "why". I have found many things that I could have done better or different in many aspects of my pregnancy and motherhood. I try not to waste too much time with the "what ifs". What we know to be true is always true until we find out it is not. Hindsight is often 20/20. So please learn from my learning curve :). Here is an article that outlines motherhood D deficiency and fetal immune system. Sure wish I had known I was deficient!

http://ajcn.nutrition.org/content/81/5/1177.1.full

3 comments:

  1. Very interesting. Thanks for sharing - I wonder how an vitamin D3 cream would work?

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  2. I will have to look for one and try it! That is a great idea! Thanks for reading!

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  3. Very interesting. Great job. My two young boys are so dry all of the time. Eczema since infant. I'm constantly conducting my own research. Thank you

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